DSPE-PEG-COOH，磷脂PEG羧基，754180-82-0

DSPE-PEG-COOH，磷脂PEG羧基，754180-82-0

产品名称：DSPE-PEG-COOH,二硬脂酰磷脂酰乙酰胺PEG羧基,754180-82-0

品牌：Ponsure

商品型号：PS2-CME1

中文名称：二硬脂酰磷脂酰乙酰胺-聚乙二醇-羧基

英文名称：1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl(polyethylene glycol)]

分子量（PEG）：1000,2000,3400,5000,10000

性状：固体到粉末（分子量决定）

储存条件：-20℃避光

保质期：一年复测

规格：0.1g,0.5g,1g,5g

应用简介：   

DSPE-PEG-COOH是芃硕生物一种带活性基团的磷脂PEG衍生物，DSPE和聚乙二醇结合具有亲水性和疏水性，聚乙二醇磷脂脂质体形成上等材料，能够用于药输送、基因转染和疫苗传递。聚乙二醇化磷脂可以明显的改善血循环时间和稳定封装药。羧基（-COOH）可以和氨基形成稳定的酰胺键，也可以和羟基发生酯化反应。

端基取代率：

DSPE：≥95%

-COOH：≥95%

溶解性：DCM,DMSO

取用保存：现配现用，将产品从冰箱中取出，置于干燥器中缓慢升至室温，打开瓶盖，取用。取用后充入惰性气体，封口膜封口，拧紧瓶盖装入自封袋，及时放入冰箱。

注意事项：DSPE-PEG-COOH因为DSPE的原因，水溶性不好，PEG分子量5000以及以上水溶性会好一些。

备注：芃硕生物所有产品仅用于的科学研究，不能用于人体用途。更多详情请咨询芃硕生物！

芃硕生物助力文献

1、

文献标题：Modulating Elasticity of Liposome for Enhanced Cancer Immunotherapy

期刊名称：ACS Nano

2、

文献标题：Sodium Assists Controlled Synthesis of Cubic Rare-Earth Oxyfluorides Nanocrystals for Information Encryption and Near-Infrared-IIb Bioimaging

期刊名称：ACS Nano

3、

文献标题：Boosting anti-PD-1 therapy with metformin-loaded macrophage-derived microparticles

期刊名称：Nature Communications

4、

文献标题：The targetable nanoparticle BAF312@cRGD-CaP-NP represses tumor growth and angiogenesis by downregulating the S1PR1/P-STAT3/VEGFA axis in triple-negative breast cancer

期刊名称：Journal of Nanobiotechnology

5、

文献标题： eptide-based semiconducting polymer nanoparticles for osteosarcoma-targeted NIR-II fluorescence/NIR-I photoacoustic dual-model imaging and photothermal/photodynamic therapies

期刊名称：Journal of Nanobiotechnology

6、

文献标题：Enhanced oral and pulmonary delivery of biomacromolecules via amplified transporter targeting

期刊名称：Journal of Controlled Release

7、

文献标题：Bioinspired butyrate-functionalized nanovehicles for targeted oraldelivery of biomacromolecular drugs

期刊名称：Journal of Controlled Release

8、

文献标题：Biomimetic Viruslike and Charge Reversible Nanoparticles to Sequentially Overcome Mucus and Epithelial Barriers for Oral Insulin Delivery

期刊名称：ACS Applied Materials & Interfaces

9、

文献标题：Sequential Release of Pooled siRNAs and Paclitaxel by Aptamer-Functionalized Shell–Core Nanoparticles to Overcome Paclitaxel Resistance of Prostate Cancer

期刊名称：ACS Applied Materials & Interfaces

10、

文献标题：Oligopeptide modified ICG/Cisplatin@CaCO3 for targeted osteosarcoma NIR-II imaging guided multimodal therapy

期刊名称：Materials & Design

11、

文献标题：Acute myocardial infarction therapy using calycosin and tanshinone co-loaded mitochondria targeted lipid-polymer hybrid nano-system: Preparation, characterization, and anti myocardial infarction activity assessment

期刊名称：Biomedicine & Pharmacotherapy

12、

文献标题：Nanoparticle BAF312@CaP-NP Overcomes Sphingosine-1-Phosphate Receptor-1-Mediated Chemoresistance Through Inhibiting S1PR1/P-STAT3 Axis in Ovarian Carcinoma

期刊名称：International Journal of Nanomedicine

13、

文献标题：Chemo-immune synergetic therapy of esophageal carcinoma: trastuzumab modified, cisplatin and fluorouracil co-delivered lipid–polymer hybrid nanoparticles

期刊名称：Drug Delivery

14、

文献标题：Acute myocardial infarction therapy: in vitro and in vivo evaluation of atrial natriuretic peptide and triphenylphosphonium dual ligands modified, baicalin-loaded nanoparticulate system

期刊名称：Drug Delivery

15、

文献标题：Acute myocardial infarction therapy using calycosin and tanshinone co-loaded; mitochondrion-targeted tetrapeptide and cyclic arginyl-glycyl-aspartic acid peptide co-modified lipid-polymer hybrid nano-system: preparation, characterization, and anti myocardial infarction activity assessment

期刊名称：Drug Delivery

16、

文献标题：Effect of –OH on the thermal enhancement properties of NIR-II lanthanide-doped nanoparticles in water

期刊名称：Inorganic Chemistry Frontiers

17、

文献标题：Paclitaxel-loaded magnetic nanocrystals for tumor neovascular-targeted theranostics: an amplifying synergistic therapy combining magnetic hyperthermia with chemotherapy

期刊名称：Nanoscale

18、

文献标题：Angiopep-2-functionalized nanoparticles enhance transport of protein drugs across intestinal epithelia by self-regulation of targeted receptors

期刊名称：Biomaterials Science